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Maya Rudolph

Maya Rudolph is about to be “Up All Night” with a baby for the fourth time. The actress, 40, is expecting baby No. 4 with longtime partner Paul Thomas Anderson, 42, according to The Hollywood Reporter. 

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The “Saturday Night Live” alum and her director beau are already parents to Pearl, 7, Lucille, 3, and Jack, 19 months.

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The pregnancy news is the latest twist in the ongoing “Up All Night” saga at NBC.

After replacing their showrunner and changing the plot of the Lorne Michaels-produced show (Ava, played by Maya, is now unemployed after her talk show was canceled, leaving Reagan, played by Christina Applegate, also unemployed and trying to find her footing as a stay-at-home mom), execs had reportedly decided to switch the sitcom to a multi-cam, live audience format.

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According to THR, the show’s scribes initially planned to write Maya’s pregnancy into Ava’s ever-changing storyline, but are now said to be seeking new jobs instead, following the exit of series star Christina Applegate, who announced she was leaving the floundering show last week.

“It’s been a great experience working on ‘Up All Night’, but the show has taken a different creative direction and I decided it was best for me to move on to other endeavors,” she said in a statement to Access Hollywood at the time. “Working with Lorne Michaels has been a dream come true and I am grateful he brought me into his TV family. I will miss the cast, producers and crew, and wish them the best always.”

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Additionally, Will Arnett (who plays Christina’s “Up All Night” on-screen husband), is in high demand for new pilots from CBS’ Les Moonves and ABC, but neither Will nor Maya have been released from their NBC contracts, according to THR.